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Posts with tag #Sleep architecture

Gut serotonin staying in the gut, walled off from the brain by the blood-brain barrier

Daylight, brain serotonin, and the gut's separate pool

Feb 26, 2026 | 7 min read

Morning light reaches brain serotonin through the eye. The gut's serotonin does not commute upstairs to become a mood.

#Dopamine #Sleep architecture
A sleep hypnogram with the largest hormone pulse sitting on slow-wave sleep

Growth hormone waits for deep sleep, not for an early bedtime

Feb 12, 2026 | 7 min read

The big growth-hormone pulse rides slow-wave sleep. Going to bed early does nothing if that deep sleep never arrives.

#Sleep architecture #Cortisol
A morning glucose curve sitting higher after a short night than after a full one

How a short night changes the next morning's glucose

Jan 8, 2026 | 7 min read

A short night raises the morning cortisol signal and makes the same breakfast harder for insulin to clear.

#Cortisol #Sleep architecture
2026 - Substrate Notes

Independent notes on human biochemistry. Written for curious readers, not exam panels.

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